Kettleshulme is a village and former civil parish, now in the parish of Kettleshulme and Lyme Handley, in the Cheshire East district, in the ceremonial county of Cheshire, England. The village is close to the border with Derbyshire, on the B5470 road from Whaley Bridge to Macclesfield in the valley of the Todd Brook, a tributary of the River Goyt. In 2001 the parish had a population of 353.