Lea Laboratory is a historic laboratory building located on the original campus of Wake Forest College at Wake Forest, North Carolina. It was designed by noted Baltimore architect John Appleton Wilson (1851–1927) and built in 1887–1888. It consists of a two-story pedimented central brick block, three bays wide and seven deep flanked by one-story pedimented brick wings. The building has a blend of Colonial Revival and Victorian design elements. It is the oldest remaining building on the original campus of Wake Forest University, now Southeastern Baptist Theological Seminary, and was one of the first chemical laboratories constructed on a Southern college campus.