Neuro-sama is an artificial intelligence VTuber and chatbot that livestreams on her creator's Twitch channel "vedal987". Her speech and personality are powered by an artificial intelligence (AI) system which utilizes a large language model, allowing her to communicate with viewers in the stream's chat. She was created by a computer programmer and AI developer named Vedal, who had the idea of an AI VTuber by combining a large language model with a computer-animated avatar. Her avatars, or models, are designed by the VTuber Anny, of the channel "annytf". She debuted on Twitch on 19 December 2022. As of January 2025, Neuro-sama is the seventh most-subscribed channel on Twitch of all time.