Newberry College Historic District is a national historic district located on the campus of Newberry College at Newberry, Newberry County, South Carolina. The district encompasses four contributing buildings and are Smeltzer Hall (1877), Keller Hall (1895), Holland Hall, and Derrick Hall (1925). Smeltzer Hall and Keller Hall reflect the Italianate, and Holland and Derrick Halls reflect the Neo-Classical and Colonial Revival styles.