The Palazzo Piccolomini, also known as the Palazzo Todeschini Piccolomini is a Renaissance-style palace in the city of Siena, region of Tuscany, Italy. It is located on the Banchi di Sotto, at the corner with Via Rinaldini; uphill and west of the church of San Martino, the Loggia del Papa, and the Palazzo delle Papesse, which also built by a Piccolomini family member. The palace houses the State Archives of Siena.