Poughkeepsie, officially the Town of Poughkeepsie, is a town in Dutchess County, New York, United States. As of the 2020 United States Census, the population was 45,471. The name is derived from the native compound Uppuqui-ipis-ing, from Uppuqui meaning "lodge-covered", plus ipis meaning "little water", plus ing meaning "place", all of which translates to "the reed-covered lodge by the little water place". This later evolved into Apokeepsing, then into Poughkeepsing, and finally Poughkeepsie.