Santo Domingo Church, formally known as the National Shrine of Our Lady of the Holy Rosary of La Naval de Manila, is a Roman Catholic parish church and national shrine in Quezon City, Metro Manila in the Philippines. It is under the jurisdiction of the Diocese of Cubao. Dedicated to Mary, mother of Jesus under her title Our Lady of the Most Holy Rosary — La Naval de Manila, it was founded by the Dominicans in 1587.