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Semaglutide

Anti-diabetic and anti-obesity medication

Semaglutide is an anti-diabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management. It is a peptide similar to the hormone glucagon-like peptide-1 (GLP-1), modified with a side chain. It can be administered by subcutaneous injection or taken orally. It is sold by Novo Nordisk under the brand names Ozempic and Rybelsus for diabetes, and under the brand name Wegovy for weight management and weight loss.

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  • 1970sJens Juul Holst and Joel Habener began research on the GLP-1 hormone in relation to duodenal ulcer disease.
  • 1988Jens Juul Holst and Joel Habener discovered GLP-1's significant potency.
  • 1993Michael Nauck managed to infuse GLP-1 into people with type 2 diabetes, stimulating insulin and inhibiting glucagon.
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