Southoe is a small village and former civil parish, now in the parish of Southoe and Midloe, in Cambridgeshire, England. Southoe lies approximately 6 miles (10 km) south-west of Huntingdon on the A1. Southoe is situated within Huntingdonshire which is a non-metropolitan district of Cambridgeshire as well as being a historic county of England. In 1931 the parish had a population of 211.