Triazoledione
Phenylpiperazine compound / From Wikipedia, the free encyclopedia
Triazoledione (developmental code name BMS-180492) is a phenylpiperazine compound and a major metabolite of the antidepressant nefazodone.[2][3] It is active, but with substantially reduced potency compared to nefazodone (approximately one-seventh).[3][2] As such, it has been suggested that it is unlikely that triazoledione contributes significantly to the pharmacology of nefazodone.[3] However, triazoledione may reach concentrations as great as 10 times those of nefazodone, and hence could still be a significant contributor to its therapeutic effects.[2]
Quick Facts Clinical data, Other names ...
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Other names | BMS-180492 |
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Elimination half-life | 18 hours[1] |
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Formula | C23H28ClN5O3 |
Molar mass | 457.96 g·mol−1 |
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