الگو:PBB/3156الگوی ویکیمدیا / From Wikipedia, the free encyclopedia اطلاعات اجمالی 3-hydroxy-3-methylglutaryl-CoA reductase, ساختارهای موجود ...3-hydroxy-3-methylglutaryl-CoA reductase بانک داده پروتئین rendering based on 1dq8. ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 1DQ8, 1DQ9, 1DQA, 1HW8, 1HW9, 1HWI, 1HWJ, 1HWK, 1HWL, 2Q1L, 2Q6B, 2Q6C, 2R4F, 3BGL, 3CCT, 3CCW, 3CCZ, 3CD0, 3CD5, 3CD7, 3CDA, 3CDB شاخصهانماد ژن HMGCR; LDLCQ3شناسههای بیرونی OMIM: 142910 MGI: 96159 HomoloGene: 30994 ChEMBL: 402 GeneCards: HMGCR GeneEC number 1.1.1.34 هستیشناسی ژن Molecular function • hydroxymethylglutaryl-CoA reductase (NADPH) activity • protein binding • hydroxymethylglutaryl-CoA reductase activity • protein homodimerization activity • coenzyme binding • protein phosphatase 2A binding • NADPH binding Cellular component • intracellular • peroxisomal membrane • endoplasmic reticulum • endoplasmic reticulum membrane • integral component of membrane Biological process • cholesterol biosynthetic process • ubiquinone metabolic process • aging • response to nutrient • isoprenoid biosynthetic process • visual learning • negative regulation of striated muscle cell apoptotic process • positive regulation of cardiac muscle cell apoptotic process • coenzyme A metabolic process • positive regulation of stress-activated MAPK cascade • negative regulation of MAP kinase activity • cellular lipid metabolic process • small molecule metabolic process • myoblast differentiation • response to ethanol • negative regulation of vasodilation • positive regulation of skeletal muscle tissue development • positive regulation of smooth muscle cell proliferation • protein tetramerization • oxidation-reduction process • negative regulation of wound healing • negative regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of ERK1 and ERK2 cascade Sources: Amigo / QuickGO الگوی بیان RNA دادهای بیان مرجع بیشتراورتولوگگونهها انسان موشآنتره 3156 15357آنسامبل ENSG00000113161 ENSMUSG00000021670UniProt P04035 Q01237RefSeq (mRNA) NM_000859 NM_008255RefSeq (protein) NP_000850 NP_032281موقعیت (UCSC) Chr 5:75.34 – 75.36 Mb Chr 13:96.65 – 96.67 Mbجستجوی پابمد نبوبستن
اطلاعات اجمالی 3-hydroxy-3-methylglutaryl-CoA reductase, ساختارهای موجود ...3-hydroxy-3-methylglutaryl-CoA reductase بانک داده پروتئین rendering based on 1dq8. ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 1DQ8, 1DQ9, 1DQA, 1HW8, 1HW9, 1HWI, 1HWJ, 1HWK, 1HWL, 2Q1L, 2Q6B, 2Q6C, 2R4F, 3BGL, 3CCT, 3CCW, 3CCZ, 3CD0, 3CD5, 3CD7, 3CDA, 3CDB شاخصهانماد ژن HMGCR; LDLCQ3شناسههای بیرونی OMIM: 142910 MGI: 96159 HomoloGene: 30994 ChEMBL: 402 GeneCards: HMGCR GeneEC number 1.1.1.34 هستیشناسی ژن Molecular function • hydroxymethylglutaryl-CoA reductase (NADPH) activity • protein binding • hydroxymethylglutaryl-CoA reductase activity • protein homodimerization activity • coenzyme binding • protein phosphatase 2A binding • NADPH binding Cellular component • intracellular • peroxisomal membrane • endoplasmic reticulum • endoplasmic reticulum membrane • integral component of membrane Biological process • cholesterol biosynthetic process • ubiquinone metabolic process • aging • response to nutrient • isoprenoid biosynthetic process • visual learning • negative regulation of striated muscle cell apoptotic process • positive regulation of cardiac muscle cell apoptotic process • coenzyme A metabolic process • positive regulation of stress-activated MAPK cascade • negative regulation of MAP kinase activity • cellular lipid metabolic process • small molecule metabolic process • myoblast differentiation • response to ethanol • negative regulation of vasodilation • positive regulation of skeletal muscle tissue development • positive regulation of smooth muscle cell proliferation • protein tetramerization • oxidation-reduction process • negative regulation of wound healing • negative regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of ERK1 and ERK2 cascade Sources: Amigo / QuickGO الگوی بیان RNA دادهای بیان مرجع بیشتراورتولوگگونهها انسان موشآنتره 3156 15357آنسامبل ENSG00000113161 ENSMUSG00000021670UniProt P04035 Q01237RefSeq (mRNA) NM_000859 NM_008255RefSeq (protein) NP_000850 NP_032281موقعیت (UCSC) Chr 5:75.34 – 75.36 Mb Chr 13:96.65 – 96.67 Mbجستجوی پابمد نبوبستن