血清応答因子

SRF
PDBに登録されている構造
PDB	オルソログ検索: RCSB PDBe PDBj
PDBのIDコード一覧
	1HBX, 1K6O, 1SRS
識別子
記号	SRF, MCM1, serum response factor
外部ID	OMIM: 600589 MGI: 106658 HomoloGene: 31135 GeneCards: SRF
遺伝子の位置 (ヒト)
染色体	6番染色体 (ヒト)
終点	43,181,506 bp
遺伝子の位置 (マウス)
染色体	17番染色体 (マウス)
終点	46,867,101 bp
RNA発現パターン
	; ;
	さらなる参照発現データ
遺伝子オントロジー
分子機能	• protein dimerization activity; • DNA-binding transcription factor activity; • DNA-binding transcription activator activity, RNA polymerase II-specific; • RNA polymerase II general transcription initiation factor activity; • primary miRNA binding; • 転写因子結合; • RNA polymerase II cis-regulatory region sequence-specific DNA binding; • protein homodimerization activity; • serum response element binding; • クロマチン結合; • 血漿タンパク結合; • DNA結合; • sequence-specific DNA binding; • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; • chromatin DNA binding; • transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; • cis-regulatory region sequence-specific DNA binding; • DNA-binding transcription factor activity, RNA polymerase II-specific; • ヒストンデアセチラーゼ結合; • RNA polymerase II-specific DNA-binding transcription factor binding;
細胞の構成要素	• 細胞質; • 細胞核; • 核質;
生物学的プロセス	• dorsal aorta morphogenesis; • 気管支軟骨発生; • muscle cell cellular homeostasis; • lung smooth muscle development; • regulation of water loss via skin; • transcription by RNA polymerase II; • stress fiber assembly; • cell migration involved in sprouting angiogenesis; • platelet activation; • cardiac myofibril assembly; • heart looping; • 細胞老化; • face development; • regulation of cell adhesion; • 長期抑圧; • neuron projection development; • morphogenesis of an epithelial sheet; • positive regulation of filopodium assembly; • primitive streak formation; • cellular response to glucose stimulus; • negative regulation of cell population proliferation; • response to cytokine; • regulation of transcription, DNA-templated; • heart trabecula formation; • actin filament organization; • 胸腺発生; • angiogenesis involved in wound healing; • 血小板形成; • neuron development; • in utero embryonic development; • transcription, DNA-templated; • positive regulation of transcription, DNA-templated; • 心臓発生; • positive regulation of cell differentiation; • branching involved in blood vessel morphogenesis; • positive regulation of axon extension; • positive regulation of smooth muscle contraction; • 気管軟骨発生; • 毒性物質への反応; • positive regulation of pri-miRNA transcription by RNA polymerase II; • positive regulation of transcription by glucose; • regulation of smooth muscle cell differentiation; • epithelial structure maintenance; • associative learning; • skin morphogenesis; • positive regulation of DNA-binding transcription factor activity; • epithelial cell-cell adhesion; • neuron migration; • positive regulation of transcription initiation from RNA polymerase II promoter; • eyelid development in camera-type eye; • 甲状腺発生; • negative regulation of amyloid-beta clearance; • negative regulation of cell migration; • developmental growth; • hematopoietic stem cell differentiation; • 原腸形成; • trophectodermal cell differentiation; • positive thymic T cell selection; • ホルモンへの反応; • cell-matrix adhesion; • sarcomere organization; • actin cytoskeleton organization; • megakaryocyte development; • 低酸素症への反応; • lung morphogenesis; • mesoderm formation; • cardiac vascular smooth muscle cell differentiation; • mRNA transcription by RNA polymerase II; • 多細胞個体の発生; • tangential migration from the subventricular zone to the olfactory bulb; • 長期記憶; • contractile actin filament bundle assembly; • bicellular tight junction assembly; • leukocyte differentiation; • 海馬発生; • positive regulation of transcription by RNA polymerase II; • erythrocyte development; • negative regulation of pri-miRNA transcription by RNA polymerase II; • 前脳発生; • cell-cell adhesion;
	出典:Amigo / QuickGO
オルソログ
	6722
	20807
	ENSG00000112658
	ENSMUSG00000015605
	P11831,A0A024RD16
	Q9JM73
	NM_003131; NM_001292001
	NM_020493
	NP_001278930; NP_003122; NP_003122.1
	NP_065239
	ウィキデータ
閲覧/編集ヒト	閲覧/編集マウス

血清応答因子（けっせいおうとういんし、英: serum response factor、略称: SRF）は、転写因子として機能するタンパク質である^[5]。

概要 SRF, PDBに登録されている構造 ...

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血清応答因子

機能

臨床的意義

相互作用

出典

関連文献

関連項目

外部リンク

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