α-辅肌动蛋白3维基百科,自由的 encyclopedia α-辅肌动蛋白3是存在于肌原纤维内的一种蛋白质.其作用是固定不同的肌动蛋白。α-辅肌动蛋白3是由ACTN3基因来表达的。 Quick Facts 已知的结构, PDB ...Α-辅肌动蛋白3已知的结构PDB直系同源搜索: PDBe RCSB PDBID列表1TJT、1WKU、3LUE识别号别名ACTN3;, actinin alpha 3 (gene/pseudogene), ACTN3D, actinin alpha 3外部IDOMIM:102574 MGI:99678 GeneCards:ACTN3 基因位置(人类)染色体11号染色体[1]基因座11q13.2起始66,546,395 bp[1]终止66,563,334 bp[1]基因位置(小鼠)染色体小鼠19号染色体[2]基因座19 A|19 4.12 cM起始4,911,244 bp[2]终止4,927,937 bp[2]RNA表达模式查阅更多表达数据基因本体分子功能• calcium ion binding• protein homodimerization activity• transmembrane transporter binding• 金属离子结合• integrin binding• 血浆蛋白结合• actin binding• structural constituent of muscle细胞组分• 细胞质基质• 伪足• 粘着斑• 胞内• 微丝• 外排体生物学过程• regulation of apoptotic process• regulation of aerobic respiration• negative regulation of glycolytic process• negative regulation of calcineurin-NFAT signaling cascade• transition between fast and slow fiber• positive regulation of glucose catabolic process to lactate via pyruvate• focal adhesion assembly• muscle filament sliding• skeletal muscle atrophy• response to denervation involved in regulation of muscle adaptation• negative regulation of oxidative phosphorylation• positive regulation of skeletal muscle tissue growth• regulation of the force of skeletal muscle contraction• negative regulation of cold-induced thermogenesisSources:Amigo / QuickGO直系同源物种人类小鼠Entrez8911474EnsemblENSG00000248746ENSMUSG00000006457UniProtQ08043O88990mRNA序列NM_001104NM_001258371NM_013456蛋白序列NP_001095NP_001245300NP_038484基因位置(UCSC)Chr 11: 66.55 – 66.56 MbChr 19: 4.91 – 4.93 MbPubMed查找[3][4]维基数据查看/编辑人类查看/编辑小鼠Close
α-辅肌动蛋白3是存在于肌原纤维内的一种蛋白质.其作用是固定不同的肌动蛋白。α-辅肌动蛋白3是由ACTN3基因来表达的。 Quick Facts 已知的结构, PDB ...Α-辅肌动蛋白3已知的结构PDB直系同源搜索: PDBe RCSB PDBID列表1TJT、1WKU、3LUE识别号别名ACTN3;, actinin alpha 3 (gene/pseudogene), ACTN3D, actinin alpha 3外部IDOMIM:102574 MGI:99678 GeneCards:ACTN3 基因位置(人类)染色体11号染色体[1]基因座11q13.2起始66,546,395 bp[1]终止66,563,334 bp[1]基因位置(小鼠)染色体小鼠19号染色体[2]基因座19 A|19 4.12 cM起始4,911,244 bp[2]终止4,927,937 bp[2]RNA表达模式查阅更多表达数据基因本体分子功能• calcium ion binding• protein homodimerization activity• transmembrane transporter binding• 金属离子结合• integrin binding• 血浆蛋白结合• actin binding• structural constituent of muscle细胞组分• 细胞质基质• 伪足• 粘着斑• 胞内• 微丝• 外排体生物学过程• regulation of apoptotic process• regulation of aerobic respiration• negative regulation of glycolytic process• negative regulation of calcineurin-NFAT signaling cascade• transition between fast and slow fiber• positive regulation of glucose catabolic process to lactate via pyruvate• focal adhesion assembly• muscle filament sliding• skeletal muscle atrophy• response to denervation involved in regulation of muscle adaptation• negative regulation of oxidative phosphorylation• positive regulation of skeletal muscle tissue growth• regulation of the force of skeletal muscle contraction• negative regulation of cold-induced thermogenesisSources:Amigo / QuickGO直系同源物种人类小鼠Entrez8911474EnsemblENSG00000248746ENSMUSG00000006457UniProtQ08043O88990mRNA序列NM_001104NM_001258371NM_013456蛋白序列NP_001095NP_001245300NP_038484基因位置(UCSC)Chr 11: 66.55 – 66.56 MbChr 19: 4.91 – 4.93 MbPubMed查找[3][4]维基数据查看/编辑人类查看/编辑小鼠Close