C5a受体

C5a受体
识别号
别名	C5AR1；, C5A, C5AR, C5R1, CD88, complement component 5a receptor 1, C5a receptor, complement C5a receptor 1
外部ID	OMIM：113995 MGI：88232 HomoloGene：20413 GeneCards：C5AR1
基因位置（人类）
染色体	19号染色体
终止	47,322,066 bp
基因位置（小鼠）
染色体	小鼠7号染色体
终止	15,993,465 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• complement component C5a binding; • signal transducer activity; • complement receptor activity; • complement component C5a receptor activity; • G protein-coupled receptor activity;
细胞组分	• integral component of membrane; • 膜; • 细胞膜; • apical part of cell; • integral component of plasma membrane; • cell surface; • basolateral plasma membrane; • cytoplasmic vesicle; • secretory granule membrane;
生物学过程	• negative regulation of neuron apoptotic process; • positive regulation of epithelial cell proliferation; • mRNA transcription by RNA polymerase II; • activation of phospholipase C activity; • neutrophil chemotaxis; • positive regulation of angiogenesis; • 趋化性; • cellular defense response; • response to lipopolysaccharide; • animal organ regeneration; • 免疫反应; • response to peptidoglycan; • positive regulation of ERK1 and ERK2 cascade; • positive regulation of neutrophil chemotaxis; • complement receptor mediated signaling pathway; • sensory perception of chemical stimulus; • positive regulation of vascular endothelial growth factor production; • cell proliferation in hindbrain; • positive regulation of macrophage chemotaxis; • 信号转导; • defense response to Gram-positive bacterium; • 细胞凋亡; • regulation of complement activation; • inflammatory response; • phospholipase C-activating G protein-coupled receptor signaling pathway; • neutrophil degranulation; • leukocyte migration; • cell chemotaxis; • positive regulation of cytosolic calcium ion concentration; • G protein-coupled receptor signaling pathway; • complement component C5a signaling pathway; • 认知; • regulation of astrocyte activation; • presynapse organization; • regulation of amyloid-beta clearance; • regulation of tau-protein kinase activity; • regulation of microglial cell activation;
	Sources:Amigo / QuickGO
直系同源
	728
	12273
	ENSG00000197405
	ENSMUSG00000049130
	P21730
	P30993
	NM_001736
	NM_001173550; NM_007577
	NP_001727
	NP_001167021; NP_031603
	维基数据
查看/编辑人类	查看/编辑小鼠

C5a受体（英语：C5a receptor或称补体成分5a受体1，complement component 5a receptor 1，C5AR1或CD88，Cluster of Differentiation 88）是一种与补体C5a（英语：Complement component 5a）相结合的G蛋白偶联受体^[5]。

事实速览 C5a受体, 识别号 ...

[5]

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[2]

[3]

[4]

C5a受体

细胞

另见

参考文献

延伸阅读

外部链接

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