L-谷氨酸-天门冬氨酸转运体

L-谷氨酸-天门冬氨酸转运体
识别号
别名	SLC1A3；, EA6, EAAT1, GLAST, GLAST1, solute carrier family 1 member 3
外部ID	OMIM：600111 MGI：99917 HomoloGene：20882 GeneCards：SLC1A3
相关疾病
	episodic ataxia type 6
为以下药物的标靶
	DL-TBOA
基因位置（人类）
染色体	5号染色体
终止	36,688,334 bp
基因位置（小鼠）
染色体	小鼠15号染色体
终止	8,740,248 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• amino acid binding; • symporter activity; • glutamate binding; • L-glutamate transmembrane transporter activity; • amino acid transmembrane transporter activity; • high-affinity glutamate transmembrane transporter activity; • acidic amino acid transmembrane transporter activity; • glutamate:sodium symporter activity; • 金属离子结合;
细胞组分	• integral component of membrane; • cell projection; • 膜; • 细胞膜; • cell surface; • soma; • neuron projection; • cell periphery; • integral component of plasma membrane;
生物学过程	• 化学性突触传递; • gamma-aminobutyric acid biosynthetic process; • glutamate biosynthetic process; • neuromuscular process controlling balance; • response to light stimulus; • cell morphogenesis involved in neuron differentiation; • cranial nerve development; • response to antibiotic; • ion transport; • 听觉; • glutamate secretion; • auditory behavior; • neurotransmitter uptake; • response to wounding; • positive regulation of synaptic transmission; • glutamate metabolic process; • L-glutamate import; • amino acid transport; • D-aspartate import across plasma membrane; • potassium ion transmembrane transport; • L-glutamate import across plasma membrane; • L-aspartate import across plasma membrane; • chloride transmembrane transport; • L-glutamate transmembrane transport;
	Sources:Amigo / QuickGO
直系同源
	6507
	20512
	ENSG00000079215
	ENSMUSG00000005360
	P43003
	P56564
	NM_001166695; NM_001166696; NM_001289939; NM_001289940; NM_004172
	NM_148938
	NP_001160167; NP_001160168; NP_001276868; NP_001276869; NP_004163
	NP_683740
	维基数据
查看/编辑人类	查看/编辑小鼠