CYP2D6

Cytochrome P450, family 2, subfamily D, polypeptide 6
Cytochrome P450, family 2, subfamily D, polypeptide 6
	PDB基於2f9q的渲染圖
有效結構
PDB	直系同源檢索：PDBe, RCSB
PDB查詢代碼列表
	2F9Q, 3QM4, 3TBG, 3TDA, 4WNT, 4WNU, 4WNV, 4WNW
標識
代號	CYP2D6; CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1
擴展標識	遺傳學：124030 鼠基因：1929474 同源基因：133550 GeneCards: CYP2D6 Gene
EC編號	1.14.14.1
基因本體論描述
分子功能	· monooxygenase activity; · iron ion binding; · drug binding; · arachidonic acid epoxygenase activity; · steroid hydroxylase activity; · oxidoreductase activity; · oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; · oxygen binding; · heme binding; · aromatase activity;
細胞成分	· cytoplasm; · mitochondrion; · endoplasmic reticulum; · endoplasmic reticulum membrane;
生物過程	· xenobiotic metabolic process; · steroid metabolic process; · coumarin metabolic process; · alkaloid metabolic process; · alkaloid catabolic process; · monoterpenoid metabolic process; · drug metabolic process; · arachidonic acid metabolic process; · isoquinoline alkaloid metabolic process; · drug catabolic process; · exogenous drug catabolic process; · small molecule metabolic process; · heterocycle metabolic process; · negative regulation of binding; · oxidation-reduction process; · oxidative demethylation; · negative regulation of cellular organofluorine metabolic process;
	Sources: Amigo / QuickGO
RNA表達模式
	更多表達數據
直系同源體
物種	人類
Entrez	1565
Ensembl	ENSG00000100197
UniProt	P10635
mRNA序列	NM_000106
蛋白序列	NP_000097
基因位置	Chr 22:; 42.13 – 42.13 Mb
PubMed查詢	[1]
	閱; 論; 編;

細胞色素 P450 2D6（cytochrome P450 2D6，CYP2D6）是一種由人類CYP2D6基因編碼的酶。CYP2D6主要合成而顯現於肝臟，並且也表現在中樞神經系統中，包括黑質。

事实速览 Cytochrome P450, family 2, subfamily D, polypeptide 6, 有效結構 ...

CYP2D6

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