人體肌肉骨骼系統或肌肉骨骼系統，簡稱肌骨系統（英語：Human musculoskeletal system，也作locomotor system，曾稱activity system[1]）是一種器官系統，通過為人體提供結構、支撐、穩定、與運動的能力使肌肉與骨骼系統得到運用。
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