MLL (基因)

髓樣/淋巴樣或混合世系白血病（三胸同源物，果蠅）
髓樣/淋巴樣或混合世系白血病（三胸同源物，果蠅）
	PDB rendering based on 2j2s.
有效結構
PDB	直系同源檢索：PDBe, RCSB
PDB查詢代碼列表
	2AGH, 2J2S, 2JYI, 2KKF, 2KU7, 2KYU, 2LXS, 2LXT, 2W5Y, 2W5Z, 3EG6, 3EMH, 3LQH, 3LQI, 3LQJ, 3P4F, 3U85, 3U88, 4ESG, 4GQ6
標識
代號	MLL; ALL-1; CXXC7; HRX; HTRX1; KMT2A; MLL/GAS7; MLL1A; TET1-MLL; TRX1; WDSTS
擴展標識	遺傳學：159555 鼠基因：96995 同源基因：4338 ChEMBL: 1293299 GeneCards: MLL Gene
EC編號	2.1.1.43
基因本體論描述
分子功能	· AT DNA binding; · sequence-specific DNA binding transcription factor activity; · protein binding; · zinc ion binding; · histone methyltransferase activity (H3-K4 specific); · identical protein binding; · protein homodimerization activity; · transcription regulatory region DNA binding; · unmethylated CpG binding; · histone acetyl-lysine binding;
細胞成分	· nucleus; · histone methyltransferase complex; · MLL1 complex;
生物過程	· transcription from RNA polymerase II promoter; · protein complex assembly; · apoptotic process; · positive regulation of transporter activity; · embryonic hemopoiesis; · histone H4-K16 acetylation; · positive regulation of transcription, DNA-dependent; · positive regulation of transcription from RNA polymerase II promoter; · histone H3-K4 methylation; · histone H3-K4 trimethylation; · positive regulation of cellular response to drug;
	Sources: Amigo / QuickGO
RNA表達模式
	更多表達數據
直系同源體
物種	人類
Entrez	4297
Ensembl	ENSG00000118058
UniProt	Q03164
mRNA序列	NM_001197104
蛋白序列	NP_001184033
基因位置	Chr 11:; 118.31 – 118.4 Mb
PubMed查詢	[1]
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