人类人工染色体(Human artificial chromosome,HAC)是一种小型染色体,可作为载体搭载一些基因,并作为人类细胞中额外的染色体(第47个),使这些基因表现于人类体内。此种人工染色体可载有约600到1000万的碱基对。HAC最早是发表于1997年。
参见
参考文献
- Formation of de novo centromeres and construction of first-generation human artificial microchromosomes (页面存档备份,存于互联网档案馆) in Nature Genetics 15, 345 - 355 (1997) Harrington and Bokkelen et al.
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