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去炎松

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去炎松
系统(IUPAC)命名名称
(11β,16α)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
临床数据
商品名Kenalog
Drugs.comMonograph
妊娠分级
  • AU: A
  • US: C (不排除有风险的可能)
给药途径Oral, topical, IM, intra-articular, intrasynovial
合法状态
合法状态
药代动力学数据
蛋白结合度68%
代谢Hepatic
生物半衰期88 minutes
排泄Fecal and renal
识别信息
CAS注册号124-94-7  ✓
ATC代码A01AC01 C05AA12, D07AB09, H02AB08, R01AD11, R03BA06, S01BA05
PubChemCID 31307
IUPHAR/BPS英语IUPHAR/BPS2870
DrugBankDB00620 ✓
ChemSpider29046 ✓
UNII1ZK20VI6TY ✓
KEGGD00385 ✓
ChEBICHEBI:9667 ☒N
ChEMBL英语ChEMBLCHEMBL1451 ✓
其他名称
Click show to see
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
化学信息
化学式C21H27FO6
摩尔质量394.434 g/mol

去炎松(英语:Triamcinolone又叫氟羟氢化泼尼松曲安西龙)是长效合成的皮质类固醇,可口服、注射、吸入或制成软膏外用。可用来治疗湿疹银屑病关节炎过敏、溃疡性大肠炎(Ulcerative colitis)、红斑性狼疮交感性眼炎、巨大细胞动脉炎(Giant cell arteritis)、葡萄膜炎(Uveitis)、眼炎的治疗,玻璃体切除时的呈像及预防哮喘等,但其无法在哮喘发作后作出有效治疗[1][2][3]

参考文献

  1. ^ Triamcinolone - Drugs.com. [2011-12-06]. (原始内容存档于2017-07-16). 
  2. ^ Triamcinolone Inhalation - Drugs.com. [2011-12-06]. (原始内容存档于2016-04-09). 
  3. ^ Alcon Receives FDA Approval of Triesence Injectable Triamcinolone Suspension for Use in Eye Surgery - Drugs.com. [2011-12-06]. (原始内容存档于2017-02-02). 
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去炎松
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