For faster navigation, this Iframe is preloading the Wikiwand page for 负氧离子洞.




负氧离子洞(英语:oxyanion hole)指的是酶的活性部分中能够稳定去质子化的氧或醇盐上的过渡态负电荷[1]的空穴。通常由共轭酰胺骨架或带正电荷的残基组成。





  1. ^ L, Stryer; JM, Berg; JL, Tymoczko. Biochemistry 5th. San Francisco: W.H. Freeman. 2002 [2019-04-07]. ISBN 978-0-7167-4955-4. (原始内容存档于2014-03-11). 
  2. ^ Simón, Luis; Goodman, Jonathan M. Enzyme Catalysis by Hydrogen Bonds: The Balance between Transition State Binding and Substrate Binding in Oxyanion Holes. doi:10.1021/jo901503d. 
  3. ^ Robert Ménard. Andrew C. Storer. Oxyanion Hole Interactions in Serine and Cysteine Proteases. Biological Chemistry Hoppe-Seyler. 1992, 2: 393–400. doi:10.1515/bchm3.1992.373.2.393. 
  4. ^ Kursula Petri. The Catalytic Cycle of Biosynthetic Thiolase: A Conformational Journey of an Acetyl Group through Four Binding Modes and Two Oxyanion Holes‡ 52 (December 1, 2002). Juha Ojala,Anne-Marie Lambeir,Rik K. Wierenga: 15543–15556. ISSN 0006-2960. doi:10.1021/bi0266232. 
{{bottomLinkPreText}} {{bottomLinkText}}
Listen to this article

This browser is not supported by Wikiwand :(
Wikiwand requires a browser with modern capabilities in order to provide you with the best reading experience.
Please download and use one of the following browsers:

This article was just edited, click to reload
This article has been deleted on Wikipedia (Why?)

Back to homepage

Please click Add in the dialog above
Please click Allow in the top-left corner,
then click Install Now in the dialog
Please click Open in the download dialog,
then click Install
Please click the "Downloads" icon in the Safari toolbar, open the first download in the list,
then click Install

Install Wikiwand

Install on Chrome Install on Firefox
Don't forget to rate us

Tell your friends about Wikiwand!

Gmail Facebook Twitter Link

Enjoying Wikiwand?

Tell your friends and spread the love:
Share on Gmail Share on Facebook Share on Twitter Share on Buffer

Our magic isn't perfect

You can help our automatic cover photo selection by reporting an unsuitable photo.

This photo is visually disturbing This photo is not a good choice

Thank you for helping!

Your input will affect cover photo selection, along with input from other users.