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辅酶

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辅酶(Coenzyme)A
辅酶(Coenzyme)A
辅酶的空间填充模型──烟酰胺腺嘌呤二核苷酸(烟酰胺腺嘌呤二核苷酸).
辅酶的空间填充模型──烟酰胺腺嘌呤二核苷酸烟酰胺腺嘌呤二核苷酸).

辅酶(英语:coenzyme)是指酶的一种辅因子,为酶催化活性所必需,且与酶蛋白结合松散的小分子量非蛋白复合有机分子。辅酶本身不是酶的组分,也无催化作用,但在酶促反应中有传递电子、原子或某些功能基团的作用。

辅酶大多源自于化水溶性维生素和其他有机必需营养素(如ATP就是一种辅酶[1][2]),在大多数情况下,可通过透析或其他方法将将辅酶除去。

辅酶被消耗在其帮助的反应上,如NADH辅酶被氧化还原反应转化至NAD+。但辅酶是会再产生的,且其在细胞内的浓度会维持在一稳定的程度。 辅酶的一特殊子集为辅基。其辅因子(或称辅助因子)会紧紧黏在酵素上,且不会在反应中被消耗。辅基包含有钼蝶呤、硫辛胺和生物素

酶蛋白与辅酶单独存在时,一般无催化能力,只有二者结合成完整的分子时,才具有活性 ,此完整的酶分子称为全酶。

参考

  1. ^ 存档副本. [2021-12-16]. (原始内容存档于2021-12-16). 
  2. ^ 存档副本. [2021-12-16]. (原始内容存档于2021-12-16). 

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辅酶
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