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LINE1

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LINE1(也称作L1或LINE-1)是DNA转座子长散在核元件(Long interspersed nuclear elements,LINEs)的一种,L1约占人类基因组的17%[1]

在人类基因组中,大部分的L1都是失活的,但仍保持着反转录转座的能力[2]

参考文献

  1. ^ International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature. Feb 2001, 409 (6822): 860–921. PMID 11237011. doi:10.1038/35057062. 
  2. ^ Ostertag, Eric M.; Kazazian Jr, Haig H. Biology of Mammalian L1 Retrotransposons. Annual Review of Genetics. December 2001, 35 (1): 501–538. doi:10.1146/annurev.genet.35.102401.091032. 
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LINE1
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