For faster navigation, this Iframe is preloading the Wikiwand page for P73.

P73

维基百科,自由的百科全书

P73
Protein TP73 PDB 1cok.png
已知的结构
PDB直系同源搜索: PDBe RCSB
识别号
别名TP73;, P73, tumor protein p73, CILD47
外部IDOMIM601990 MGI1336991 HomoloGene:3960 GeneCardsTP73
基因位置(人类
1号染色体
染色体1号染色体[1]
1号染色体
P73的基因位置
P73的基因位置
基因座1p36.32起始3,652,516 bp[1]
终止3,736,201 bp[1]
RNA表达模式
PBB GE TP73 220804 s at fs.png
查阅更多表达数据
直系同源
物种人类小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_001126330
​NM_001126331
​NM_011642

蛋白序列

NP_001119802
​NP_001119803
​NP_035772

基因位置​(UCSC)Chr 1: 3.65 – 3.74 MbChr 4: 154.14 – 154.22 Mb
PubMed​查找[3][4]
维基数据
查看/编辑人类查看/编辑小鼠

p73,又称为TP73,是p53蛋白家族的成员之一,以其分子量为73kD而得名,存在多种转录变体。p73的结构和功能均与p53类似,为肿瘤抑制蛋白,能调控细胞增殖并促进细胞凋亡。过表达p73的细胞增殖会停止。

参见

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000078900 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000029026 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
{{bottomLinkPreText}} {{bottomLinkText}}
P73
Listen to this article

This browser is not supported by Wikiwand :(
Wikiwand requires a browser with modern capabilities in order to provide you with the best reading experience.
Please download and use one of the following browsers:

This article was just edited, click to reload
This article has been deleted on Wikipedia (Why?)

Back to homepage

Please click Add in the dialog above
Please click Allow in the top-left corner,
then click Install Now in the dialog
Please click Open in the download dialog,
then click Install
Please click the "Downloads" icon in the Safari toolbar, open the first download in the list,
then click Install
{{::$root.activation.text}}

Install Wikiwand

Install on Chrome Install on Firefox
Don't forget to rate us

Tell your friends about Wikiwand!

Gmail Facebook Twitter Link

Enjoying Wikiwand?

Tell your friends and spread the love:
Share on Gmail Share on Facebook Share on Twitter Share on Buffer

Our magic isn't perfect

You can help our automatic cover photo selection by reporting an unsuitable photo.

This photo is visually disturbing This photo is not a good choice

Thank you for helping!


Your input will affect cover photo selection, along with input from other users.