模板:PBB/183维基媒体模板 / 维基百科,自由的 encyclopedia Quick Facts 血管紧张肽原(丝氨酸蛋白酶抑制剂), 有效结构 ...血管紧张肽原(丝氨酸蛋白酶抑制剂) 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 1N9U, 1N9V, 2JP8, 2WXW, 2X0B 标识代号 AGT; ANHU; FLJ92595; FLJ97926; SERPINA8扩展标识 遗传学:106150 鼠基因:87963 同源基因:14 GeneCards: AGT Gene 基因本体论描述 分子功能 · serine-type endopeptidase inhibitor activity · hormone activity · hormone activity · protein binding · growth factor activity · acetyltransferase activator activity · type 1 angiotensin receptor binding · type 2 angiotensin receptor binding 细胞成分 · extracellular region · extracellular region · extracellular region · extracellular space · extracellular space · extracellular space · soluble fraction · cytoplasmic part 生物过程 · ovarian follicle rupture · regulation of cell growth · blood vessel development · positive regulation of cytokine production · kidney development · blood vessel remodeling · angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure · renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure · regulation of blood volume by renin-angiotensin · renin-angiotensin regulation of aldosterone production · regulation of renal output by angiotensin · regulation of blood vessel size by renin-angiotensin · brain renin-angiotensin system · cellular sodium ion homeostasis · cell-matrix adhesion · G-protein coupled receptor protein signaling pathway · G-protein signaling, coupled to cGMP nucleotide second messenger · activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger · nitric oxide mediated signal transduction · cell-cell signaling · excretion · establishment of blood-nerve barrier · regulation of blood pressure · negative regulation of cell proliferation · response to cold · response to salt stress · positive regulation of activation of JAK2 kinase activity · positive regulation of endothelial cell migration · positive regulation of cardiac muscle hypertrophy · positive regulation of macrophage derived foam cell differentiation · positive regulation of cholesterol esterification · negative regulation of endopeptidase activity · regulation of norepinephrine secretion · positive regulation of phosphatidylinositol 3-kinase cascade · response to muscle activity involved in regulation of muscle adaptation · regulation of vasoconstriction · regulation of proteolysis · extracellular matrix organization · negative regulation of cell growth · peristalsis · positive regulation of cellular protein metabolic process · positive regulation of NAD(P)H oxidase activity · low-density lipoprotein particle remodeling · positive regulation of multicellular organism growth · regulation of cell proliferation · hormone metabolic process · drinking behavior · positive regulation of apoptosis · positive regulation of catalytic activity · positive regulation of MAPKKK cascade · negative regulation of neuron apoptosis · cellular lipid metabolic process · positive regulation of fatty acid biosynthetic process · positive regulation of epidermal growth factor receptor signaling pathway · positive regulation of transcription, DNA-dependent · positive regulation of organ growth · astrocyte activation · positive regulation of fibroblast proliferation · regulation of long-term neuronal synaptic plasticity · smooth muscle cell proliferation · positive regulation of inflammatory response · positive regulation of peptidyl-tyrosine phosphorylation · positive regulation of NF-kappaB transcription factor activity · smooth muscle cell differentiation · negative regulation of nerve growth factor receptor signaling pathway · positive regulation of protein tyrosine kinase activity · positive regulation of branching involved in ureteric bud morphogenesis · positive regulation of reactive oxygen species metabolic process Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 183 11606Ensembl ENSG00000135744 ENSMUSG00000031980UniProt P01019 Q3UTR7mRNA序列 NM_000029.3 NM_007428.3蛋白序列 NP_000020.1 NP_031454.3基因位置 Chr 1:230.84 – 230.85 Mb Chr 8:127.08 – 127.09 MbPubMed查询 [1] [2]查论编Close
Quick Facts 血管紧张肽原(丝氨酸蛋白酶抑制剂), 有效结构 ...血管紧张肽原(丝氨酸蛋白酶抑制剂) 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 1N9U, 1N9V, 2JP8, 2WXW, 2X0B 标识代号 AGT; ANHU; FLJ92595; FLJ97926; SERPINA8扩展标识 遗传学:106150 鼠基因:87963 同源基因:14 GeneCards: AGT Gene 基因本体论描述 分子功能 · serine-type endopeptidase inhibitor activity · hormone activity · hormone activity · protein binding · growth factor activity · acetyltransferase activator activity · type 1 angiotensin receptor binding · type 2 angiotensin receptor binding 细胞成分 · extracellular region · extracellular region · extracellular region · extracellular space · extracellular space · extracellular space · soluble fraction · cytoplasmic part 生物过程 · ovarian follicle rupture · regulation of cell growth · blood vessel development · positive regulation of cytokine production · kidney development · blood vessel remodeling · angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure · renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure · regulation of blood volume by renin-angiotensin · renin-angiotensin regulation of aldosterone production · regulation of renal output by angiotensin · regulation of blood vessel size by renin-angiotensin · brain renin-angiotensin system · cellular sodium ion homeostasis · cell-matrix adhesion · G-protein coupled receptor protein signaling pathway · G-protein signaling, coupled to cGMP nucleotide second messenger · activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger · nitric oxide mediated signal transduction · cell-cell signaling · excretion · establishment of blood-nerve barrier · regulation of blood pressure · negative regulation of cell proliferation · response to cold · response to salt stress · positive regulation of activation of JAK2 kinase activity · positive regulation of endothelial cell migration · positive regulation of cardiac muscle hypertrophy · positive regulation of macrophage derived foam cell differentiation · positive regulation of cholesterol esterification · negative regulation of endopeptidase activity · regulation of norepinephrine secretion · positive regulation of phosphatidylinositol 3-kinase cascade · response to muscle activity involved in regulation of muscle adaptation · regulation of vasoconstriction · regulation of proteolysis · extracellular matrix organization · negative regulation of cell growth · peristalsis · positive regulation of cellular protein metabolic process · positive regulation of NAD(P)H oxidase activity · low-density lipoprotein particle remodeling · positive regulation of multicellular organism growth · regulation of cell proliferation · hormone metabolic process · drinking behavior · positive regulation of apoptosis · positive regulation of catalytic activity · positive regulation of MAPKKK cascade · negative regulation of neuron apoptosis · cellular lipid metabolic process · positive regulation of fatty acid biosynthetic process · positive regulation of epidermal growth factor receptor signaling pathway · positive regulation of transcription, DNA-dependent · positive regulation of organ growth · astrocyte activation · positive regulation of fibroblast proliferation · regulation of long-term neuronal synaptic plasticity · smooth muscle cell proliferation · positive regulation of inflammatory response · positive regulation of peptidyl-tyrosine phosphorylation · positive regulation of NF-kappaB transcription factor activity · smooth muscle cell differentiation · negative regulation of nerve growth factor receptor signaling pathway · positive regulation of protein tyrosine kinase activity · positive regulation of branching involved in ureteric bud morphogenesis · positive regulation of reactive oxygen species metabolic process Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 183 11606Ensembl ENSG00000135744 ENSMUSG00000031980UniProt P01019 Q3UTR7mRNA序列 NM_000029.3 NM_007428.3蛋白序列 NP_000020.1 NP_031454.3基因位置 Chr 1:230.84 – 230.85 Mb Chr 8:127.08 – 127.09 MbPubMed查询 [1] [2]查论编Close