模板:PBB/6469维基媒体模板 / 维基百科,自由的 encyclopedia Quick Facts 音猬因子, 有效结构 ...音猬因子 3D structure of the signaling domain of the murine Sonic hedgehog from PDB 1vhh 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 3HO5, 3M1N, 3MXW 标识代号 SHH; HHG1; HLP3; HPE3; MCOPCB5; SMMCI; TPT; TPTPS扩展标识 遗传学:600725 鼠基因:98297 同源基因:30961 GeneCards: SHH Gene 基因本体论描述 分子功能 · glycoprotein binding · signal transducer activity · patched binding · calcium ion binding · protein binding · glycosaminoglycan binding · peptidase activity · zinc ion binding · laminin-1 binding 细胞成分 · extracellular region · extracellular space · extracellular space · membrane fraction · nucleus · endoplasmic reticulum · Golgi apparatus · plasma membrane · cell surface · transport vesicle · extracellular matrix · membrane raft 生物过程 · patterning of blood vessels · vasculogenesis · metanephros development · branching involved in ureteric bud morphogenesis · response to hypoxia · cell fate specification · neural crest cell migration · neural tube formation · vasculature development · heart looping · positive regulation of neuroblast proliferation · positive regulation of mesenchymal cell proliferation · osteoblast development · lymphoid progenitor cell differentiation · endocytosis · signal transduction · smoothened signaling pathway · positive regulation of hh target transcription factor activity · cell-cell signaling · determination of left/right symmetry · pattern specification process · ectoderm development · neuroblast proliferation · axon guidance · central nervous system development · ventral midline development · hindgut morphogenesis · digestive tract mesoderm development · heart development · blood coagulation · androgen metabolic process · cell death · positive regulation of cell proliferation · embryo development · anterior/posterior pattern formation · dorsal/ventral pattern formation · response to organic nitrogen · oligodendrocyte development · striated muscle tissue development · positive regulation of skeletal muscle cell proliferation · myotube differentiation · intein-mediated protein splicing · spinal cord dorsal/ventral patterning · ventral spinal cord interneuron specification · dorsal/ventral neural tube patterning · smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation · positive regulation of cerebellar granule cell precursor proliferation · telencephalon regionalization · establishment of cell polarity · regulation of proteolysis · positive regulation of Wnt receptor signaling pathway · lung development · embryonic limb morphogenesis · negative regulation of cell migration · male genitalia development · prostate gland development · regulation of epithelial cell differentiation · thyroid gland development · forebrain development · midbrain development · hindbrain development · pancreas development · hair follicle morphogenesis · response to estradiol stimulus · negative regulation of proteasomal ubiquitin-dependent protein catabolic process · response to retinoic acid · T cell differentiation in thymus · positive regulation of T cell differentiation in thymus · positive regulation of immature T cell proliferation in thymus · embryonic forelimb morphogenesis · embryonic hindlimb morphogenesis · regulation of cell proliferation · negative regulation of T cell proliferation · positive regulation of protein import into nucleus · odontogenesis of dentine-containing tooth · embryonic digit morphogenesis · camera-type eye development · negative regulation of apoptosis · CD4-positive or CD8-positive, alpha-beta T cell lineage commitment · tongue morphogenesis · skin development · positive thymic T cell selection · negative thymic T cell selection · intermediate filament organization · myoblast differentiation · response to ethanol · negative regulation of cell differentiation · positive regulation of transcription, DNA-dependent · positive regulation of transcription from RNA polymerase II promoter · positive regulation of photoreceptor cell differentiation · positive regulation of alpha-beta T cell differentiation · negative regulation of alpha-beta T cell differentiation · cell development · thymus development · embryonic digestive tract morphogenesis · embryonic organ development · developmental growth · embryonic foregut morphogenesis · positive regulation of skeletal muscle tissue development · organ formation · neuron fate commitment · response to axon injury · embryonic skeletal system development · positive regulation of oligodendrocyte differentiation · branching morphogenesis of a tube · male genitalia morphogenesis · inner ear development · formation of anatomical boundary · stem cell development · positive regulation of striated muscle cell differentiation · Bergmann glial cell differentiation · palate development · limb development · limb bud formation · positive regulation of penile erection · lung epithelium development · trachea morphogenesis · branching involved in salivary gland morphogenesis · bud outgrowth involved in lung branching · right lung development · left lung development · lung lobe morphogenesis · lung-associated mesenchyme development · primary prostatic bud elongation · prostate epithelial cord elongation · salivary gland cavitation · epithelial cell proliferation involved in salivary gland morphogenesis · regulation of prostatic bud formation · epithelial-mesenchymal signaling involved in prostate gland development · positive regulation of epithelial cell proliferation involved in prostate gland development · regulation of mesenchymal cell proliferation involved in prostate gland development · mesenchymal smoothened signaling pathway involved in prostate gland development · artery development · mesenchymal cell proliferation involved in lung development · sclerotome development · positive regulation of oligodendrocyte progenitor proliferation · cellular response to lithium ion · metanephric mesenchymal cell proliferation involved in metanephros development · regulation of mesenchymal cell proliferation involved in ureter development · multicellular structure septum development · negative regulation of canonical Wnt receptor signaling pathway · negative regulation of ureter smooth muscle cell differentiation · positive regulation of ureter smooth muscle cell differentiation · negative regulation of kidney smooth muscle cell differentiation · positive regulation of kidney smooth muscle cell differentiation Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 6469 20423Ensembl ENSG00000164690 ENSMUSG00000002633UniProt Q15465 Q8C765mRNA序列 NM_000193.2 NM_009170.3蛋白序列 NP_000184.1 NP_033196.1基因位置 Chr 7:155.59 – 155.6 Mb Chr 5:28.78 – 28.79 MbPubMed查询 [1] [2]查论编Close
Quick Facts 音猬因子, 有效结构 ...音猬因子 3D structure of the signaling domain of the murine Sonic hedgehog from PDB 1vhh 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 3HO5, 3M1N, 3MXW 标识代号 SHH; HHG1; HLP3; HPE3; MCOPCB5; SMMCI; TPT; TPTPS扩展标识 遗传学:600725 鼠基因:98297 同源基因:30961 GeneCards: SHH Gene 基因本体论描述 分子功能 · glycoprotein binding · signal transducer activity · patched binding · calcium ion binding · protein binding · glycosaminoglycan binding · peptidase activity · zinc ion binding · laminin-1 binding 细胞成分 · extracellular region · extracellular space · extracellular space · membrane fraction · nucleus · endoplasmic reticulum · Golgi apparatus · plasma membrane · cell surface · transport vesicle · extracellular matrix · membrane raft 生物过程 · patterning of blood vessels · vasculogenesis · metanephros development · branching involved in ureteric bud morphogenesis · response to hypoxia · cell fate specification · neural crest cell migration · neural tube formation · vasculature development · heart looping · positive regulation of neuroblast proliferation · positive regulation of mesenchymal cell proliferation · osteoblast development · lymphoid progenitor cell differentiation · endocytosis · signal transduction · smoothened signaling pathway · positive regulation of hh target transcription factor activity · cell-cell signaling · determination of left/right symmetry · pattern specification process · ectoderm development · neuroblast proliferation · axon guidance · central nervous system development · ventral midline development · hindgut morphogenesis · digestive tract mesoderm development · heart development · blood coagulation · androgen metabolic process · cell death · positive regulation of cell proliferation · embryo development · anterior/posterior pattern formation · dorsal/ventral pattern formation · response to organic nitrogen · oligodendrocyte development · striated muscle tissue development · positive regulation of skeletal muscle cell proliferation · myotube differentiation · intein-mediated protein splicing · spinal cord dorsal/ventral patterning · ventral spinal cord interneuron specification · dorsal/ventral neural tube patterning · smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation · positive regulation of cerebellar granule cell precursor proliferation · telencephalon regionalization · establishment of cell polarity · regulation of proteolysis · positive regulation of Wnt receptor signaling pathway · lung development · embryonic limb morphogenesis · negative regulation of cell migration · male genitalia development · prostate gland development · regulation of epithelial cell differentiation · thyroid gland development · forebrain development · midbrain development · hindbrain development · pancreas development · hair follicle morphogenesis · response to estradiol stimulus · negative regulation of proteasomal ubiquitin-dependent protein catabolic process · response to retinoic acid · T cell differentiation in thymus · positive regulation of T cell differentiation in thymus · positive regulation of immature T cell proliferation in thymus · embryonic forelimb morphogenesis · embryonic hindlimb morphogenesis · regulation of cell proliferation · negative regulation of T cell proliferation · positive regulation of protein import into nucleus · odontogenesis of dentine-containing tooth · embryonic digit morphogenesis · camera-type eye development · negative regulation of apoptosis · CD4-positive or CD8-positive, alpha-beta T cell lineage commitment · tongue morphogenesis · skin development · positive thymic T cell selection · negative thymic T cell selection · intermediate filament organization · myoblast differentiation · response to ethanol · negative regulation of cell differentiation · positive regulation of transcription, DNA-dependent · positive regulation of transcription from RNA polymerase II promoter · positive regulation of photoreceptor cell differentiation · positive regulation of alpha-beta T cell differentiation · negative regulation of alpha-beta T cell differentiation · cell development · thymus development · embryonic digestive tract morphogenesis · embryonic organ development · developmental growth · embryonic foregut morphogenesis · positive regulation of skeletal muscle tissue development · organ formation · neuron fate commitment · response to axon injury · embryonic skeletal system development · positive regulation of oligodendrocyte differentiation · branching morphogenesis of a tube · male genitalia morphogenesis · inner ear development · formation of anatomical boundary · stem cell development · positive regulation of striated muscle cell differentiation · Bergmann glial cell differentiation · palate development · limb development · limb bud formation · positive regulation of penile erection · lung epithelium development · trachea morphogenesis · branching involved in salivary gland morphogenesis · bud outgrowth involved in lung branching · right lung development · left lung development · lung lobe morphogenesis · lung-associated mesenchyme development · primary prostatic bud elongation · prostate epithelial cord elongation · salivary gland cavitation · epithelial cell proliferation involved in salivary gland morphogenesis · regulation of prostatic bud formation · epithelial-mesenchymal signaling involved in prostate gland development · positive regulation of epithelial cell proliferation involved in prostate gland development · regulation of mesenchymal cell proliferation involved in prostate gland development · mesenchymal smoothened signaling pathway involved in prostate gland development · artery development · mesenchymal cell proliferation involved in lung development · sclerotome development · positive regulation of oligodendrocyte progenitor proliferation · cellular response to lithium ion · metanephric mesenchymal cell proliferation involved in metanephros development · regulation of mesenchymal cell proliferation involved in ureter development · multicellular structure septum development · negative regulation of canonical Wnt receptor signaling pathway · negative regulation of ureter smooth muscle cell differentiation · positive regulation of ureter smooth muscle cell differentiation · negative regulation of kidney smooth muscle cell differentiation · positive regulation of kidney smooth muscle cell differentiation Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 6469 20423Ensembl ENSG00000164690 ENSMUSG00000002633UniProt Q15465 Q8C765mRNA序列 NM_000193.2 NM_009170.3蛋白序列 NP_000184.1 NP_033196.1基因位置 Chr 7:155.59 – 155.6 Mb Chr 5:28.78 – 28.79 MbPubMed查询 [1] [2]查论编Close