訊息傳遞轉接蛋白

訊息傳遞轉接蛋白或訊息傳遞銜接蛋白（英語：Signal transducing adaptor proteins）是訊息傳遞通路中的重要蛋白質。轉接蛋白上有著各種能與其它蛋白結合的結構域，能形成各種信號複合體。這些蛋白質往往本身缺乏酶的活性^[1]，而是通過特異性的蛋白-蛋白交互作用形成蛋白質複合體來活化下游信號通路。常見的轉接蛋白有MyD88、Grb2和SHC1等。

Src相關轉接蛋白Skap2

基因

編碼轉接蛋白的基因有：

• BCAR3 – Breast cancer anti-estrogen resistance protein 3
• GRAP – GRB2-related adaptor protein
• GRAP2 – GRB2-related adaptor protein 2
• LDLRAP1 – low-density lipoprotein receptor adaptor protein 1
• NCK1 – NCK adaptor protein 1
• NCK2 – NCK adaptor protein 2
• NOS1AP – nitric oxide synthase 1 (neuronal) adaptor protein
• PIK3AP1 – phosphoinositide-3-kinase adaptor protein 1
• SH2B1 – SH2B adaptor protein 1
• SH2B2 – SH2B adaptor protein 2
• SH2B3 – SH2B adaptor protein 3
• SH2D3A -SH2 domain containing 3A
• SH2D3C – SH2 domain containing 3C
• SHB – Src homology 2 domain containing adaptor protein B
• SLC4A1AP – solute carrier family 4 (anion exchanger), member 1, adaptor protein
• GAB2 – GRB2-associated binding protein 2