白血球介素-13

白細胞介素13
已知的結構
PDB	直系同源搜尋: PDBe RCSB
PDBID列表
	1GA3、1IJZ、1IK0、3BPO、3G6D、3L5W、3L5X、3LB6、4I77、4PS4、5E4E
識別號
別名	IL13；, IL-13, P600, interleukin 13
外部ID	OMIM：147683 MGI：96541 HomoloGene：1649 GeneCards：IL13
相關疾病
	氣喘、霍奇金淋巴瘤、銀屑病
基因位置（小鼠）
染色體	小鼠11號染色體
終止	53,525,529 bp
RNA表現模式
	查閱更多表現資料
基因本體
分子功能	• 血漿蛋白結合; • 細胞因子受體結合; • 細胞因子活性; • interleukin-13 receptor binding;
細胞組分	• 細胞質; • external side of plasma membrane; • 細胞外區域; • 細胞外空間;
生物學過程	• 內皮細胞凋亡過程的負調控; • negative regulation of complement-dependent cytotoxicity; • negative regulation of transforming growth factor beta production; • positive regulation of lung goblet cell differentiation; • response to mechanical stimulus; • response to nicotine; • positive regulation of release of sequestered calcium ion into cytosol; • microglial cell activation; • negative regulation of NAD(P)H oxidase activity; • cellular response to mechanical stimulus; • response to lipopolysaccharide; • negative regulation of lung ciliated cell differentiation; • positive regulation of ion transport; • 免疫反應; • positive regulation of protein secretion; • positive regulation of connective tissue growth factor production; • positive regulation of pancreatic stellate cell proliferation; • response to ethanol; • inflammatory response; • regulation of proton transport; • positive regulation of smooth muscle cell proliferation; • negative regulation of neuron death; • positive regulation of immunoglobulin production; • positive regulation of B cell proliferation; • positive regulation of macrophage activation; • positive regulation of mast cell degranulation; • cellular response to cytokine stimulus; • positive regulation of tyrosine phosphorylation of STAT protein; • regulation of signaling receptor activity; • cytokine-mediated signaling pathway; • positive regulation of gene expression; • positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
直系同源
	3596
	16163
	ENSG00000169194
	ENSMUSG00000020383
	P35225
	P20109
	NM_002188
	NM_008355
	NP_002179; NP_001341920; NP_001341921; NP_001341922
	NP_032381
	維基資料
檢視/編輯人類	檢視/編輯小鼠

白血球介素-13（英語：Interleukin-13，縮寫IL-13）是一種細胞因子，由人類基因 IL13 編碼^[5]^[6]^[7]。IL-13結構上與白血球介素-4（IL-4）非常相似，有25%的序列相似性^[8]，都能與由白介素-4受體α亞基（CD124）與白介素-13受體α1（CD213a1）組成的白介素-13受體結合。

快速預覽 白細胞介素13, 已知的結構 ...

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白血球介素-13

參考資料

外部連結

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