CD29

CD29
已知的結構
PDB	直系同源搜尋: PDBe RCSB
PDBID列表
	4WK4、3G9W、3T9K、3VI3、3VI4、4DX9、4WJK、4WK0、4WK2
識別號
別名	ITGB1；, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, integrin subunit beta 1
外部ID	OMIM：135630 MGI：96610 HomoloGene：22999 GeneCards：ITGB1
基因位置（人類）
染色體	10號染色體
終止	33,005,792 bp
基因位置（小鼠）
染色體	小鼠8號染色體
終止	129,459,681 bp
RNA表現模式
	查閱更多表現資料
基因本體
分子功能	• virus receptor activity; • 金屬離子結合; • integrin binding; • 血漿蛋白結合; • laminin binding; • cell adhesion molecule binding; • collagen binding involved in cell-matrix adhesion; • coreceptor activity; • 蛋白酶結合; • fibronectin binding; • actin binding; • C-X3-C chemokine binding; • protein heterodimerization activity; • 大分子錯合物結合; • cadherin binding; • signaling receptor activity;
細胞組分	• 細胞質; • 核內體; • 膜; • 黑色素體; • ruffle; • integrin alpha8-beta1 complex; • 突觸; • ruffle membrane; • integrin complex; • 細胞質的核周區域; • cell projection; • 樹突棘; • cell surface; • 分裂溝; • integrin alpha7-beta1 complex; • 外排體; • 板狀偽足; • integral component of membrane; • recycling endosome; • integrin alpha1-beta1 complex; • 肌間盤; • 絲狀偽足; • 神經肌肉接點; • receptor complex; • 細胞膜; • integrin alpha11-beta1 complex; • myelin sheath abaxonal region; • synaptic membrane; • integrin alpha10-beta1 complex; • 細胞連接; • integrin alpha2-beta1 complex; • 肌膜; • external side of plasma membrane; • cytoplasmic vesicle; • integrin alpha3-beta1 complex; • 脂筏模型; • 粘著斑; • glial cell projection; • Schaffer collateral - CA1 synapse; • glutamatergic synapse; • integral component of synaptic membrane; • 大分子複合體;
生物學過程	• leukocyte cell-cell adhesion; • cell migration involved in sprouting angiogenesis; • stress fiber assembly; • 病毒進入; • B cell differentiation; • neuron projection development; • transforming growth factor beta receptor signaling pathway; • regulation of collagen catabolic process; • negative regulation of cell differentiation; • cardiac muscle cell differentiation; • cellular response to low-density lipoprotein particle stimulus; • in utero embryonic development; • cell-substrate adhesion; • positive regulation of GTPase activity; • regulation of immune response; • viral process; • dendrite morphogenesis; • cell fate specification; • G1期; • heterotypic cell-cell adhesion; • extracellular matrix organization; • cell-cell adhesion mediated by integrin; • cellular defense response; • 細胞粘附; • formation of radial glial scaffolds; • axon extension; • leukocyte tethering or rolling; • integrin-mediated signaling pathway; • cell-matrix adhesion; • sarcomere organization; • negative regulation of anoikis; • leukocyte migration; • homophilic cell adhesion via plasma membrane adhesion molecules; • visual learning; • calcium-independent cell-matrix adhesion; • cardiac muscle tissue development; • negative regulation of Rho protein signal transduction; • receptor internalization; • regulation of cell cycle; • positive regulation of cell population proliferation; • positive regulation of apoptotic process; • mesodermal cell differentiation; • 細胞遷移; • germ cell migration; • cell adhesion mediated by integrin; • basement membrane organization; • positive regulation of protein localization to plasma membrane; • G1/S transition of mitotic cell cycle; • 吞噬作用; • cytokine-mediated signaling pathway; • cell projection organization; • lamellipodium assembly; • positive regulation of angiogenesis; • modulation of chemical synaptic transmission; • positive regulation of protein kinase B signaling; • positive regulation of signaling receptor activity; • positive regulation of cell migration;
	Sources:Amigo / QuickGO
直系同源
	3688
	16412
	ENSG00000150093
	ENSMUSG00000025809
	P05556
	P09055
NM_002211; NM_033666; NM_033667; NM_033668; NM_033669;
	NM_133376
	NM_010578
	NP_002202; NP_391988; NP_596867
	NP_034708
	維基資料
檢視/編輯人類	檢視/編輯小鼠

整聯蛋白β-1（英語：Integrin beta-1），也被稱為 CD29 是一個由人類基因 ITGB1 編碼的蛋白質^[5]。CD29是整合素極晚期抗原受體的一個亞基。它與α-3亞基形成整合素α3β1，作為神經生長因子1和絡絲蛋白的受體。在心肌和骨骼肌種，整聯蛋白β-1會選擇性表現為β-1D蛋白質異形體。

快速預覽 CD29, 已知的結構 ...

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CD29

相互作用

參考文獻

外部連結

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