Arrestin
Family of proteins / From Wikipedia, the free encyclopedia
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Arrestins (abbreviated Arr) are a small family of proteins important for regulating signal transduction at G protein-coupled receptors.[2][3] Arrestins were first discovered as a part of a conserved two-step mechanism for regulating the activity of G protein-coupled receptors (GPCRs) in the visual rhodopsin system by Hermann Kühn, Scott Hall, and Ursula Wilden[4] and in the β-adrenergic system by Martin J. Lohse and co-workers.[5][6]
Quick Facts S-antigen; retina and pineal gland (arrestin), Identifiers ...
S-antigen; retina and pineal gland (arrestin) | |||||||
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Identifiers | |||||||
Symbol | SAG | ||||||
Alt. symbols | arrestin-1 | ||||||
NCBI gene | 6295 | ||||||
HGNC | 10521 | ||||||
OMIM | 181031 | ||||||
RefSeq | NM_000541 | ||||||
UniProt | P10523 | ||||||
Other data | |||||||
Locus | Chr. 2 q37.1 | ||||||
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Quick Facts Identifiers, Symbol ...
arrestin beta 1 | |||||||
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Identifiers | |||||||
Symbol | ARRB1 | ||||||
Alt. symbols | ARR1, arrestin-2 | ||||||
NCBI gene | 408 | ||||||
HGNC | 711 | ||||||
OMIM | 107940 | ||||||
RefSeq | NM_004041 | ||||||
UniProt | P49407 | ||||||
Other data | |||||||
Locus | Chr. 11 q13 | ||||||
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Quick Facts Identifiers, Symbol ...
arrestin beta 2 | |||||||
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Identifiers | |||||||
Symbol | ARRB2 | ||||||
Alt. symbols | ARR2, arrestin-3 | ||||||
NCBI gene | 409 | ||||||
HGNC | 712 | ||||||
OMIM | 107941 | ||||||
RefSeq | NM_004313 | ||||||
UniProt | P32121 | ||||||
Other data | |||||||
Locus | Chr. 17 p13 | ||||||
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Quick Facts Identifiers, Symbol ...
arrestin 3, retinal (X-arrestin) | |||||||
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Identifiers | |||||||
Symbol | ARR3 | ||||||
Alt. symbols | ARRX, arrestin-4 | ||||||
NCBI gene | 407 | ||||||
HGNC | 710 | ||||||
OMIM | 301770 | ||||||
RefSeq | NM_004312 | ||||||
UniProt | P36575 | ||||||
Other data | |||||||
Locus | Chr. X q | ||||||
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