CDC37
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene.[5] This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone[6] with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.[7]
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Quick Facts Identifiers, Symbol ...
Cdc37 N terminal kinase binding | |||||||||
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Identifiers | |||||||||
Symbol | CDC37_N | ||||||||
Pfam | PF03234 | ||||||||
InterPro | IPR013855 | ||||||||
SCOP2 | 1us7 / SCOPe / SUPFAM | ||||||||
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