Dipyridamole
Anticoagulant drug / From Wikipedia, the free encyclopedia
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Dipyridamole (trademarked as Persantine and others) is a nucleoside transport inhibitor and a PDE3 inhibitor medication that inhibits blood clot formation[3][dead link] when given chronically and causes blood vessel dilation when given at high doses over a short time.
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Persantine, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682830 |
Routes of administration | By mouth, intravenous |
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Pharmacokinetic data | |
Bioavailability | 37–66%[1] |
Protein binding | ~99% |
Metabolism | Liver (glucuronidation)[2] |
Elimination half-life | α phase: 40 min, β phase: 10 hours |
Excretion | Biliary (95%), urine (negligible) |
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ECHA InfoCard | 100.000.340 |
Chemical and physical data | |
Formula | C24H40N8O4 |
Molar mass | 504.636 g·mol−1 |
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