Hexokinase
Class of enzymes / From Wikipedia, the free encyclopedia
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A hexokinase is an enzyme that irreversibly phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate for hexokinases, and glucose-6-phosphate is the most important product. Hexokinase possesses the ability to transfer an inorganic phosphate group from ATP to a substrate.
Quick Facts Identifiers, EC no. ...
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Quick Facts Identifiers, Symbol ...
hexokinase 1 | |||||||
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Identifiers | |||||||
Symbol | HK1 | ||||||
NCBI gene | 3098 | ||||||
HGNC | 4922 | ||||||
OMIM | 142600 | ||||||
RefSeq | NM_000188 | ||||||
UniProt | P19367 | ||||||
Other data | |||||||
Locus | Chr. 10 q22 | ||||||
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Quick Facts Identifiers, Symbol ...
hexokinase 2 | |||||||
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Identifiers | |||||||
Symbol | HK2 | ||||||
NCBI gene | 3099 | ||||||
HGNC | 4923 | ||||||
OMIM | 601125 | ||||||
RefSeq | NM_000189 | ||||||
UniProt | P52789 | ||||||
Other data | |||||||
Locus | Chr. 2 p13 | ||||||
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Quick Facts Identifiers, Symbol ...
hexokinase 3 (white cell) | |||||||
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Identifiers | |||||||
Symbol | HK3 | ||||||
NCBI gene | 3101 | ||||||
HGNC | 4925 | ||||||
OMIM | 142570 | ||||||
RefSeq | NM_002115 | ||||||
UniProt | P52790 | ||||||
Other data | |||||||
Locus | Chr. 5 q35.2 | ||||||
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Quick Facts Hexokinase_1, Identifiers ...
Hexokinase_1 | |||||||||
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Identifiers | |||||||||
Symbol | Hexokinase_1 | ||||||||
Pfam | PF00349 | ||||||||
Pfam clan | CL0108 | ||||||||
InterPro | IPR022672 | ||||||||
PROSITE | PDOC00370 | ||||||||
SCOP2 | 1cza / SCOPe / SUPFAM | ||||||||
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Quick Facts Hexokinase_2, Identifiers ...
Hexokinase_2 | |||||||||
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Identifiers | |||||||||
Symbol | Hexokinase_2 | ||||||||
Pfam | PF03727 | ||||||||
Pfam clan | CL0108 | ||||||||
InterPro | IPR022673 | ||||||||
PROSITE | PDOC00370 | ||||||||
SCOP2 | 1cza / SCOPe / SUPFAM | ||||||||
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Hexokinases should not be confused with glucokinase, which is a specific hexokinase found in the liver. All hexokinases are capable of phosphorylating several hexoses but hexokinase IV(D) is often misleadingly called glucokinase, though it is no more specific for glucose than the other mammalian isoenzymes.[3]