Kynurenine pathway
Metabolic pathway that produces the NAD coenzyme / From Wikipedia, the free encyclopedia
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The kynurenine pathway is a metabolic pathway leading to the production of nicotinamide adenine dinucleotide (NAD+).[1] Metabolites involved in the kynurenine pathway include tryptophan, kynurenine, kynurenic acid, xanthurenic acid, quinolinic acid, and 3-hydroxykynurenine.[2][3] The kynurenine pathway is responsible for about 95% of total tryptophan catabolism.[4] Disruption in the pathway is associated with certain genetic and psychiatric disorders.[5][2][6][7][8]