Nav1.7 is a sodium ion channel that in humans is encoded by the SCN9A gene.[5][6][7] It is usually expressed at high levels in two types of neurons: the nociceptive (pain) neurons at the dorsal root ganglion (DRG) and trigeminal ganglion; and sympathetic ganglion neurons, which are part of the autonomic (involuntary) nervous system.[8][9]
Quick Facts SCN9A, Available structures ...
SCN9A |
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Identifiers |
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Aliases | SCN9A, ETHA, FEB3B, GEFSP7, HSAN2D, NE-NA, NENA, Nav1.7, PN1, SFNP, sodium voltage-gated channel alpha subunit 9 |
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External IDs | OMIM: 603415 MGI: 107636 HomoloGene: 2237 GeneCards: SCN9A |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- spinal ganglia
- stromal cell of endometrium
- trigeminal ganglion
- Achilles tendon
- right lobe of liver
- rectum
- hypothalamus
- transverse colon
- islet of Langerhans
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| Top expressed in | - olfactory epithelium
- trigeminal ganglion
- superior cervical ganglion
- median eminence
- arcuate nucleus
- supraoptic nucleus
- paraventricular nucleus of hypothalamus
- dorsomedial hypothalamic nucleus
- ventromedial nucleus
- islet of Langerhans
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| More reference expression data |
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BioGPS | |
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Wikidata |
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