Prucalopride
Drug used to treat chronic constipation / From Wikipedia, the free encyclopedia
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Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT4 receptor agonist[2] which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements.[3][4][5][6][7][8] Prucalopride was approved for medical use in the European Union in 2009,[9] in Canada in 2011,[10] in Israel in 2014,[11] and in the United States in December 2018.[12] The drug has also been tested for the treatment of chronic intestinal pseudo-obstruction.[13][14]
Quick Facts Clinical data, Trade names ...
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Trade names | Resolor, Resotran, Motegrity |
Other names | R-093877, R-108512 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a619011 |
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Routes of administration | By mouth |
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Formula | C18H26ClN3O3 |
Molar mass | 367.87 g·mol−1 |
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