Triamterene
Chemical compound / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Triamterene?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
"Ademine" redirects here. Not to be confused with adenine.
Triamterene (trade name Dyrenium among others) is a potassium-sparing diuretic often used in combination with thiazide diuretics for the treatment of high blood pressure or swelling. The combination with hydrochlorothiazide, is known as hydrochlorothiazide/triamterene.
This section needs additional citations for verification. (June 2012) |
Quick Facts Clinical data, Trade names ...
Clinical data | |
---|---|
Trade names | Dyrenium, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682337 |
Pregnancy category |
|
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 30-70% |
Protein binding | 67% |
Metabolism | hydroxylation to para-hydroxytriamterene |
Elimination half-life | 1-2 hours, active metabolite 3 hours |
Excretion | renal <50%, 21% unchanged |
Identifiers | |
| |
CAS Number |
|
PubChem CID | |
IUPHAR/BPS | |
DrugBank |
|
ChemSpider |
|
UNII | |
KEGG |
|
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.006.278 |
Chemical and physical data | |
Formula | C12H11N7 |
Molar mass | 253.269 g·mol−1 |
| |
NY (what is this?) (verify) |
Close