DCN

Protein sy'n cael ei godio yn y corff dynol gan y genyn DCN yw DCN a elwir hefyd yn Decorin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q21.33.^[2]

DCN
Dynodwyr
Cyfenwau	DCN, Dcn, DC, DSPG2, PG40, PGII, PGS2, SLRR1B, mDcn, CSCD, decorin
Dynodwyr allanol	OMIM: 125255 HomoloGene: 22430 GeneCards: DCN
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • collagen binding • protein N-terminus binding • protein kinase inhibitor activity • glycosaminoglycan binding • extracellular matrix binding • GO:0001948, GO:0016582 protein binding • RNA binding • extracellular matrix structural constituent conferring compression resistance Cydrannau o'r gell • cytoplasm • GO:0005578 extracellular matrix • lysosomal lumen • Golgi lumen • collagen type VI trimer • extracellular space • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • glycosaminoglycan metabolic process • positive regulation of mitochondrial fission • negative regulation of protein kinase activity • positive regulation of autophagy • kidney development • cytokine-mediated signaling pathway • placenta development • chondroitin sulfate biosynthetic process • response to mechanical stimulus • GO:0010260 heneiddio • extracellular matrix disassembly • extracellular matrix organization • wound healing • negative regulation of endothelial cell migration • positive regulation of macroautophagy • response to lipopolysaccharide • positive regulation of mitochondrial depolarization • animal organ morphogenesis • chondroitin sulfate catabolic process • negative regulation of angiogenesis • positive regulation of phosphatidylinositol 3-kinase signaling • peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan • negative regulation of vascular endothelial growth factor signaling pathway • dermatan sulfate biosynthetic process • skeletal muscle tissue development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • negative regulation of receptor signaling pathway via JAK-STAT Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1634	n/a
Ensembl	ENSG00000011465	n/a
UniProt	P07585	n/a
RefSeq (mRNA)	NM_001920 NM_133503 NM_133504 NM_133505 NM_133506 NM_133507	n/a
RefSeq (protein)	NP_001911 NP_598010 NP_598011 NP_598012 NP_598013 NP_598014	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DCN.

• CSCD
• PG40
• PGII
• PGS2
• DSPG2
• SLRR1B

Llyfryddiaeth

• "Role of Decorin Core Protein in Collagen Organisation in Congenital Stromal Corneal Dystrophy (CSCD). ". PLoS One. 2016. PMID 26828927.
• "Decorin: A Growth Factor Antagonist for Tumor Growth Inhibition. ". Biomed Res Int. 2015. PMID 26697491.
• "Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology. ". FEBS J. 2017. PMID 27860287.
• "Decorin Genotypes, Serum Glucose, Heart Rate, and Cerebrovascular Events: The Tampere Adult Population Cardiovascular Risk Study. ". Genet Test Mol Biomarkers. 2016. PMID 27315044.
• "Posterior amorphous corneal dystrophy caused by a de novo deletion.". Ophthalmic Genet. 2017. PMID 27096414.