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- January 15 – The Soviet Union launches Soyuz 5.
- March 3 – Apollo program: NASA launches Apollo 9 to test the lunar module.
- March 13 – Apollo program: Apollo 9 returns safely to Earth after testing the Lunar Module.
- May 16 – Venera program: Venera 5, a Soviet spaceprobe, lands on Venus.
- May 17 – Venera program: Soviet Venera 6 begins to descend into Venus', atmosphere sending back atmospheric data before being crushed by pressure.
- May 18 – Apollo program: Apollo 10 launches.
- May 22 – Apollo program: Apollo 10's lunar module flies within 15,400 m of the Moon's surface.
- May 26 – Apollo program: Apollo 10 returns to Earth after a successful eight-day test of all the components needed for the upcoming first manned Moon landing.
- July 17 – The New York Times publicly retracts its ridicule of the rocket scientist Robert H. Goddard published on 13 January 1920 which stated that spaceflight is impossible.
- July 20 – Apollo program: 20:17 UTC – The human race, represented by Neil Armstrong and Buzz Aldrin, lands on the Moon in the Apollo 11 Lunar Module Eagle. At 02:56 UTC on July 21 (22:56 ET July 20), Armstrong takes the first human step on the Moon's surface. Apollo 11 lifted off for the Moon on July 16 and returns safely on July 24.
- July 21 – Luna programme: 2 hours before the Apollo 11 lunar module lifts off from the Moon's surface, Soviet unmanned craft Luna 15, launched on July 13 and intended to return samples from the Moon, crashes in Mare Crisium.
- August 5 – Mariner program: Mariner 7 makes its closest fly-by of Mars (3,524 kilometers).
- September 20 – Comet 67P/Churyumov–Gerasimenko is identified by Soviet astronomers Klim Churyumov and Svetlana Gerasimenko.
- November 14 – Apollo program: NASA launches Apollo 12, the second manned mission to the surface of the Moon.
- November 19 – Apollo program: Apollo 12 astronauts Charles Conrad and Alan Bean land at Oceanus Procellarum ("Ocean of Storms") and become the third and fourth humans to walk on the Moon.
- Thomas D. Brock and Hudson Freeze of Indiana University publish their findings on hyperthermophilic bacteria, most notably Thermus aquaticus, a thermophilic bacterium species living at a temperature of 60-80 °C in a hot spring at Yellowstone National Park. T. aquaticus (Taq) later becomes a standard source of enzymes able to withstand higher temperatures than those from E. Coli and is significant in the history of polymerase chain reaction.
- Last Przewalski's Horse sighted in the wild, in Mongolia.
- Marked decline in common whitethroats due to Sahel drought draws attention to effects of climate on migratory species.
- April 7 – RFC 1, the first Request for Comments document from the Internet Engineering Task Force, is published.
- October 29 – The first ARPANET message is sent, between computers at the University of California, Los Angeles (UCLA) and Stanford Research Institute.
- November 21 – The first permanent ARPANET link is established, between Interface Message Processors at UCLA and Stanford.
- The laser printer is invented at Xerox by Gary Starkweather.
- CCD invented at AT&T Bell Labs, used as the electronic imager in still and video cameras.
- March – The condition diffuse panbronchiolitis is named, in Japan.
- April 4 – Surgeons Denton Cooley and Domingo Liotta implant the first temporary artificial heart.
- May 15 – A teenager known as 'Robert R.' dies in St. Louis, Missouri, of a baffling medical condition. In 1984 it will be identified as the earliest confirmed case of HIV/AIDS in North America. The first strain of the AIDS virus (HIV) has probably migrated to the United States via Haiti.
- International adoption of the diagnostic term 'Sudden infant death syndrome'.
- March 3 – Elizabeth Laird (born 1874), Canadian physicist.
- May 14 – Walter Pitts (born 1923), American logician and cognitive psychologist.
- June 24 – Willy Ley (born 1906), German American scientific populariser.
- August 8 – Otmar von Verschuer (born 1896), German eugenicist.
- August 17 – Otto Stern (born 1888), German physicist, Nobel laureate in Physics in 1943.
- September 16 – Henry Fairfield Osborn, Jr. (born 1887), American conservationist.
- September 24 – Warren Sturgis McCulloch (born 1898), American neurophysiologist and cybernetician.
- October 21 – Wacław Sierpiński (born 1882), Polish mathematician.
- November 12 – William F. Friedman (born 1891), Russian American cryptanalyst.
- "Robert H. Goddard Story". astronauticsnow. Retrieved 2019-07-19.
- Brock, Thomas D.; Freeze, Hudson (August 1969). "Thermus aquaticus gen. n. and sp. n., a nonsporulating extreme thermophile". Journal of Bacteriology. American Society for Microbiology. 98 (1): 289–297. doi:10.1128/jb.98.1.289-297.1969. PMC 249935. PMID 5781580.
- Adams, M. J.; et al. (1969-11-01). "Structure of Rhombohedral 2 Zinc Insulin Crystals". Nature. 224 (5218): 491–495. Bibcode:1969Natur.224..491A. doi:10.1038/224491a0.
- Savio, Jessica (2011-04-01). "Browsing history: A heritage site is being set up in Boelter Hall 3420, the room the first Internet message originated in". Daily Bruin. UCLA. Archived from the original on 2012-01-05. Retrieved 2012-10-29.
- Sutton, Chris (2004-09-02). "Internet Began 35 Years Ago at UCLA with First Message Ever Sent Between Two Computers". UCLA. Archived from the original on 8 March 2008.
- Reilly, Edwin D. (2003). Milestones in Computer Science and Information Technology. Greenwood Press. p. 152. ISBN 1-57356-521-0.
- Allan, Roy A. (2001). A History of the Personal Computer: the People and the Technology. Allan Publishing. ISBN 0-9689108-0-7.
starkweather laser-printer 1971 parc.
- Yamanaka, A.; Saiki, S.; Tamura, S.; Saito, K. (1969). "Problems in chronic obstructive bronchial diseases, with special reference to diffuse panbronchiolitis". Naika (in Japanese). 23 (3): 442–451. PMID 5783341.
- "AIDS Virus Came to US Via Haiti". Voice of America. 2007-10-30. Retrieved 2011-10-22.
- Carolan, Patrick L. "Sudden Infant Death Syndrome". Medscape. Retrieved 2012-01-26.
- Ostrom, J. H. (1969). "Osteology of Deinonychus antirrhopus, an unusual theropod from the Lower Cretaceous of Montana". Peabody Museum of Natural History Bulletin. 30: 1–165.
- Fastovsky, D.E.; Weishampel, D.B. (2005). "Theropoda I: Nature Red in Tooth and Claw". In Fastovsky, D.E.; Weishampel, D.B. (eds.). The Evolution and Extinction of the Dinosaurs (2nd ed.). Cambridge University Press. pp. 265–299. ISBN 978-0-521-81172-9.
- Schwarz, John H. (2000). "String Theory: The Early Years". arXiv:hep-th/0007118.
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