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Chemical compound From Wikipedia, the free encyclopedia
4-DAMP (1,1-dimethyl-4-diphenylacetoxypiperidinium iodide) is a selective muscarinic acetylcholine receptor (mAChR) M3 antagonist.[2] It is also able to antagonize M1 receptors but "prefers" M3.[3][4] It competitively binds to the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists.
Names | |
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Preferred IUPAC name
4-[(Diphenylacetyl)oxy]-1,1-dimethylpiperidin-1-ium iodide | |
Other names
4-(2,2-Diphenylacetoxy)-1,1-dimethylpiperidin-1-ium iodide | |
Identifiers | |
3D model (JSmol) |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C21H26INO2 | |
Molar mass | 451.348 g·mol−1 |
Appearance | White to beige powder[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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