Atrolysin C
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Atrolysin C (EC 3.4.24.42, Crotalus atrox metalloendopeptidase c, hemorrhagic toxin c and d) is an enzyme.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- Cleavage of His5-Leu, His10-Leu, Ala14-Leu, Tyr16-Leu and Gly23-Phe bonds in B chain of insulin. With small molecule substrates prefers hydrophobic residue at P2' and small residue such as Ala, Gly at P1
Quick Facts Identifiers, EC no. ...
Atrolysin C | |||||||||
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Identifiers | |||||||||
EC no. | 3.4.24.42 | ||||||||
CAS no. | 158886-17-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).