Brivaracetam
Medication used to treat seizures / From Wikipedia, the free encyclopedia
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Brivaracetam, sold under the brand name Briviact among others, is a chemical analog of levetiracetam, a racetam derivative with anticonvulsant (antiepileptic) properties.[5][6] It is marketed by the pharmaceutical company UCB.[7][8]
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Pronunciation | /ˌbrɪvəˈræsətəm/ BRIV-ə-RASS-ə-təm |
Trade names | Briviact, Nubriveo, Brivajoy |
AHFS/Drugs.com | Monograph |
MedlinePlus | a616027 |
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Routes of administration | By mouth, intravenous |
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Bioavailability | Nearly 100% |
Protein binding | ≤20% |
Metabolism | Hydrolysis by amidase, CYP2C19-mediated hydroxylation |
Metabolites | 3 inactive metabolites |
Elimination half-life | ≈9 hours |
Excretion | Kidneys (>95%)[4] |
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ECHA InfoCard | 100.118.642 |
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Formula | C11H20N2O2 |
Molar mass | 212.293 g·mol−1 |
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Specific rotation | [α]D −60° |
Melting point | 72 to 77 °C (162 to 171 °F) |
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A generic version of brivaracetam has been approved by the Food and Drug Administration (FDA) in the United States, but it is not yet available as a generic medication.[9][10]