Busulfan
Chemical compound / From Wikipedia, the free encyclopedia
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Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a chemotherapy drug in use since 1959. It is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation is 1,4-butanediol dimethanesulfonate.
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Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Myleran, Busilvex, Busulfex IV |
Other names | 1,4-butanediol dimethanesulfonate |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682248 |
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Routes of administration | By mouth, intravenous |
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Bioavailability | 60–80% (oral) |
Protein binding | 32.4% |
Metabolism | Liver |
Elimination half-life | 2.5 hours |
Excretion | Urine (25–60%) |
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ECHA InfoCard | 100.000.228 |
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Formula | C6H14O6S2 |
Molar mass | 246.29 g·mol−1 |
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