Canrenone
Chemical compound / From Wikipedia, the free encyclopedia
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Canrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid[3][4] of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium.[5][6][7][8] It is also an important active metabolite of spironolactone, and partially accounts for its therapeutic effects.[9][2]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Contaren, Luvion, Phanurane, Spiroletan |
Other names | Aldadiene;[1] SC-9376; RP-11614; 7α-Desthioacetyl-δ6-spironolactone; 6,7-Dehydro-7α-desthioacetylspironolactone; 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid γ-lactone |
AHFS/Drugs.com | International Drug Names |
Drug class | Antimineralocorticoid |
ATC code | |
Pharmacokinetic data | |
Protein binding | 95% |
Elimination half-life | 16.5 hours[2] |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.012.322 |
Chemical and physical data | |
Formula | C22H28O3 |
Molar mass | 340.463 g·mol−1 |
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