Clotiazepam
Chemical compound / From Wikipedia, the free encyclopedia
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Clotiazepam[3] (marketed under brand name Clozan, Distensan, Trecalmo, Rize, Rizen and Veratran) is a thienodiazepine drug which is a benzodiazepine analog. The clotiazepam molecule differs from benzodiazepines in that the benzene ring has been replaced by a thiophene ring.[4] It possesses anxiolytic,[5] skeletal muscle relaxant,[6] anticonvulsant, sedative properties.[7] Stage 2 NREM sleep is significantly increased by clotiazepam.[8]
Quick Facts Clinical data, Trade names ...
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Trade names | Veratran, Rize, Clozan |
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Routes of administration | Oral, sublingual, liquid drops |
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Bioavailability | ~90% |
Metabolism | Hepatic |
Elimination half-life | 4 hours[2] |
Excretion | Renal |
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ECHA InfoCard | 100.046.920 |
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Formula | C16H15ClN2OS |
Molar mass | 318.82 g·mol−1 |
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