Amoxicillin/clavulanic acid
Combination antibiotic medication / From Wikipedia, the free encyclopedia
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Amoxicillin/clavulanic acid, also known as co-amoxiclav or amox-clav, sold under the brand name Augmentin, among others, is an antibiotic medication used for the treatment of a number of bacterial infections.[5] It is a combination consisting of amoxicillin, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor.[5] It is specifically used for otitis media, streptococcal pharyngitis, pneumonia, cellulitis, urinary tract infections, and animal bites.[5] It is taken by mouth or by injection into a vein.[2]
Combination of | |
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Amoxicillin | Penicillin antibiotic |
Clavulanic acid | Beta-lactamase inhibitor |
Clinical data | |
Trade names | Augmentin, Clavulin, Amoclan, others[1] |
Other names | co-amoxiclav, amox-clav |
AHFS/Drugs.com | Monograph |
MedlinePlus | a685024 |
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Routes of administration | By mouth, intravenous[2] |
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Chemical and physical data | |
Formula | C24H27KN4O10S |
Molar mass | 602.66 g·mol−1 |
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Common side effects include diarrhea, vomiting, and allergic reactions.[5] It also increases the risk of yeast infections, headaches, and blood clotting problems.[2][6] It is not recommended in people with a history of a penicillin allergy.[2] It is relatively safe for use during pregnancy.[5]
Amoxicillin/clavulanic acid was approved for medical use in the United States in 1984.[5] It is on the World Health Organization's List of Essential Medicines.[7][8] The World Health Organization classifies amoxicillin/clavulanic-acid as critically important for human medicine.[9] It is available as a generic medication.[5] In 2021, it was the 115th most commonly prescribed medication in the United States, with more than 5 million prescriptions.[10][11]