Cytochrome c oxidase subunit I
Enzyme of the respiratory chain encoded by the mitochondrial genome / From Wikipedia, the free encyclopedia
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"Cox1" redirects here. Particularly in a medical context, this can also refer to cyclooxygenase-1.
Cytochrome c oxidase I (COX1) also known as mitochondrially encoded cytochrome c oxidase I (MT-CO1) is a protein that is encoded by the MT-CO1 gene in eukaryotes.[6] The gene is also called COX1, CO1, or COI.[7] Cytochrome c oxidase I is the main subunit of the cytochrome c oxidase complex. In humans, mutations in MT-CO1 have been associated with Leber's hereditary optic neuropathy (LHON), acquired idiopathic sideroblastic anemia, Complex IV deficiency, colorectal cancer, sensorineural deafness, and recurrent myoglobinuria.[8][9][10]
Quick Facts COX1, Identifiers ...
COX1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | COX1, mitochondrially encoded cytochrome c oxidase I, COI, MTCO1, Main subunit of cytochrome c oxidase, CO I, cytochrome c oxidase subunit I | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 516030 MGI: 102504 HomoloGene: 5016 GeneCards: COX1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Quick Facts Identifiers, Symbol ...
Cytochrome c oxidase subunit I | |||||||||
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Identifiers | |||||||||
Symbol | COX1 or COI | ||||||||
Pfam | PF00115 | ||||||||
InterPro | IPR000883 | ||||||||
PROSITE | PDOC00074 | ||||||||
SCOP2 | 1occ / SCOPe / SUPFAM | ||||||||
TCDB | 3.D.4 | ||||||||
OPM superfamily | 4 | ||||||||
OPM protein | 1v55 | ||||||||
CDD | cd01663 | ||||||||
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