Demecarium bromide
Chemical compound / From Wikipedia, the free encyclopedia
Not to be confused with Decamethonium.
Demecarium bromide, trade name Humorsol, is a carbamate parasympathomimetic drug that acts as an acetylcholinesterase inhibitor, and is used as a glaucoma medication. It is applied directly to the eye in order to reduce elevated intraocular pressure associated with glaucoma.[1]
Quick Facts Clinical data, Trade names ...
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Trade names | Humorsol |
Routes of administration | Topical (ophthalmic solution) |
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ECHA InfoCard | 100.000.274 |
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Formula | C32H52Br2N4O4 |
Molar mass | 716.600 g·mol−1 |
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Demecarium causes constriction of the pupil (miosis), which improves the drainage of the fluid in the eye (aqueous humour).[2] As demecarium reversibly inhibits cholinesterase, it can be administered less frequently than other parasympathomimetic drugs, such as carbachol.[3]
Commercially produced demecarium bromide solution, previously sold under the trade name Humorsol,[4] is no longer available,[3] although solutions of demecarium can be compounded.[5]