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Chemical compound From Wikipedia, the free encyclopedia
Demexiptiline (brand names Deparon, Tinoran) is a tricyclic antidepressant (TCA) used in France for the treatment of depression.[2][3] It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine.[4]
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Trade names | Deparon, Tinoran |
Routes of administration | Oral |
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Elimination half-life | 35 hours[1] |
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Formula | C18H18N2O |
Molar mass | 278.355 g·mol−1 |
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The ketone dibenzosuberenone (1) is treated with hydroxylamine (2) to give its ketoxime (3). Base-catalyzed alkylation with ClCH2CH2NHCH3 (4) yields demexiptiline.[5][6]
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