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Diatrizoate
Chemical compound / From Wikipedia, the free encyclopedia
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Diatrizoate, also known as amidotrizoate, Gastrografin, is a contrast agent used during X-ray imaging.[1] This includes visualizing veins, the urinary system, spleen, and joints, as well as computer tomography (CT scan).[1] It is given by mouth, injection into a vein, injection into the bladder, through a nasogastric tube, or rectally.[2][3]
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Trade names | Hypaque, Gastrografin, Iothalmate, others |
Other names | amidotrizoic acid, diatrizoic acid, 3,5-diacetamido-2,4,6-triiodobenzoic acid |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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ECHA InfoCard | 100.003.840 ![]() |
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Formula | C11H9I3N2O4 |
Molar mass | 613.916 g·mol−1 |
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Relatively common side effects include vomiting, diarrhea, and skin redness.[4] Other side effects include itchiness, kidney problems, low blood pressure, and allergic reactions.[1] It is not recommended in people who have an iodine allergy.[1] Diatrizoate is an iodinated ionic radiocontrast agent with high osmolality.[2]
Diatrizoate was approved for medical use in the United States in 1954.[4] It is on the World Health Organization's List of Essential Medicines.[5]